Single cell nanobiosensors for dynamic gene expression profiling in native tissue microenvironments.
نویسندگان
چکیده
A gold nanorod-locked nucleic acid nano-biosensor for dynamic single-cell gene expression analysis in living cells and tissues is developed. The nanoparticle facilitates endocytic delivery and dynamic monitoring of the gene expression in human umbilical cord endothelial cells, mouse skin tissues, mouse retina tissues, and mouse cornea tissues at the single-cell level.
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ورودعنوان ژورنال:
- Advanced materials
دوره 27 39 شماره
صفحات -
تاریخ انتشار 2015